I copied a virtual disk (actually the entire machine) for a VirtualBox VM and tried to add the machine to the GUI list. It wouldn't add because the virtual disk already existed. I ended up needing to change the UUID of the virtual disk and modify the virtual machine config file accordingly. The command to do this is:
VBoxManage.exe internalcommands sethduuid "D:\NewVM\myDisk1.vdi"
Reference (also has other commands):
Change the UUID of Virtual Disk
Changing UUID for VirtualBox Virtual Machines